Klara Ewald-Weinhold was born in Alsace. Her family moved to Hanau in 1920. Ewald-Weinhold began her art studies at the State Academy of Drawing in Hanau at the age of 17, studying under Hans Schimke, Richard Estler and Reissner. She then moved to the Kassel Art Academy for three years, working in between as a gymnastics teacher in Berlin.
She returned to Hanau in 1924 and spent over seven years as the master student of Reinhold Ewald, whom she married in 1928. She exhibited numerous times at the Hanau Academy, the New Secession in Darmstadt and in the Palais de Chaillot in Paris. A bombing raid in 1945 destroyed almost all her paintings.